| 盐酸戊乙奎醚联合地塞米松对兔爆震伤急性呼吸窘迫综合征的治疗作用 |
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| 引用本文： | 范崇熙,程庆书,汪健,朱以芳,李桂珍,张志培,李小飞.盐酸戊乙奎醚联合地塞米松对兔爆震伤急性呼吸窘迫综合征的治疗作用[J].解放军医学杂志,2011,36(11):1154-1158. |
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| 作者姓名： | 范崇熙 程庆书 汪健 朱以芳 李桂珍 张志培 李小飞 |
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| 作者单位： | 710038,西安 第四军医大学唐都医院胸外科 |
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| 基金项目： | 全军医药卫生科研基金(08G103) |
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| 摘 要： | 目的 探讨盐酸戊乙奎醚(PHC)联合地塞米松(DXM)对兔胸部爆震伤ARDS的治疗作用.方法 采用健康新西兰大白兔制作兔胸部爆震伤ARDS模型,将符合ARDS诊断标准的兔随机分为5组:B组,爆炸致ARDS组(n=10)；C组,低剂量(0.8mg/kg)PHC组(n=9)；D组,高剂量(1.5mg/kg) PHC组(n=...
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| 关 键 词： | 爆震伤 呼吸窘迫综合征 成人 盐酸戊乙奎醚 地塞米松 细胞因子类 模型 动物 |
Therapeutic effect of penehyclidine hydrochloride combined with dexamethasone on acute respiratory distress syndrome induced by blast injury in rabbits |
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| FAN Chong-xi,CHENG Qing-shu,WANG Jian,ZHU Yi-fang,LI Gui-zhen,ZHANG Zhi-pei,LI Xiao-fei.Therapeutic effect of penehyclidine hydrochloride combined with dexamethasone on acute respiratory distress syndrome induced by blast injury in rabbits[J].Medical Journal of Chinese People's Liberation Army,2011,36(11):1154-1158. |
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| Authors: | FAN Chong-xi CHENG Qing-shu WANG Jian ZHU Yi-fang LI Gui-zhen ZHANG Zhi-pei LI Xiao-fei |
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| Institution: | FAN Chong-xi,CHENG Qing-shu,WANG Jian,ZHU Yi-fang,LI Gui-zhen,ZHANG Zhi-pei,LI Xiao-fei*.Department of Thoracic Surgery,Tang du Hospital,Fourth Military Medical University,710038,Xi'an,China |
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| Abstract: | Objective To discuss the therapeutic effects of penehyclidine hydrochloride combined with dexamethasone on Acute Respiratory Distress Syndrome(ARDS) after a thoracic blast injury in rabbits.Methods Healthy New Zealand white rabbits were used to establish the ARDS model induced by a thoracic blast injury.The rabbits conforming to the diagnostic standard of ARDS were divided into 5 groups randomly: B group,ARDS caused by blast(n=10);C group,PHC(n=9) with low dose(0.8mg/kg);D group,PHC(n=9) with higher dose(1.... |
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| Keywords: | blast injuries respiratory distress syndrome adult penehyclidine hydrochloride dexamethasone cytokines models animal |
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