| 血清HE4和CA125在卵巢上皮癌诊断中的作用 |
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| 引用本文： | 段永红. 血清HE4和CA125在卵巢上皮癌诊断中的作用[J]. 中国现代医生, 2013, 0(30): 75-76,79 |
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| 作者姓名： | 段永红 |
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| 作者单位： | 湖南省邵阳医学高等专科学校附属医院妇产科,湖南邵阳422000 |
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| 摘 要： | 目的探讨血清人附睾蛋白4（HE4）和糖类抗原125（CA125）水平对卵巢上皮癌的诊断价值。方法应用酶联免疫吸附法（ELISA）和放射免疫分析法对30例卵巢上皮癌患者、30例健康女性进行血清HE4和CA125的测定。结果卵巢上皮癌患者血清HE4和CA125水平均显著高于正常人（P〈0．01）。结论检测血清HE4联合CA125的浓度可能为临床提供一种新的诊断卵巢上皮癌的方法。
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| 关 键 词： | 卵巢上皮癌 糖类抗原125 人附睾蛋白4 |
Significance of HE4 estimation in comparison with CA125 in diagnosis of epithelial ovarian cancer |
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| Affiliation: | DUA N Yonghong Department of Obstetrics and Gynecology, the Affiliated Hospital of Shaoyang Medical College, Shaoyang 422000, China |
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| Abstract: | Objective To evaluate human epididymis protein 4 （HE4）, in comparison with carbohydrate antigen 125 （CA 125） in diagnosis of epithelial ovarian cancer. Methods Serum CA125 （with ELISA） and HE4（with RIA） levels were measured in 30 patients with epithelial ovarian cancer, 30 healthy women. Results Serum HE4 and CA125 concen trations were significantly higher in the ovarian cancer patients compared with those in the healthy controls （P 〈 0.01 ）. Conclusion Measuring serum HE4 concentrations along with CA125 concentrations may provide higher accuracy for detecting epithelial ovarian cancer. |
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| Keywords: | Epithelial ovarian cancer Carbohydrate antigen125 （CA 125） Human epididymis protein 4 （HE4） |
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