危重症患者肠内外营养疗效比较

目的对比分析危重症患者肠内外营养的疗效。方法凹顾性分析112例危重症患者的临床资料．根据纳入对象营养方式小同分为肠内营养组、肠外营养组、混合营养组。另外选择单纯经口进食供能的患者30例为埘照组。比较各组治疗前和治疗后10d肝功能、。肾功能、总白蛋白、免疫功能指标等。结果肠内营养组、肠外荷养组、混合营养组总蛋白、白蛋白、前白蛋白、血红蛋白、TLC、CD4、CD4／CD8在治疗前后组内比较均冠著升高（P均〈0．05）。肠内营养和混合喂养患者IgG治疗后较治疗前湿著升高（P〈0．05），肠内营养组和混合喂养组治疗后IgG水平也够著高于肠外营养组、对照组（P〈0．05）。结论危重症患者早期给予营养支持可以预防重要脏器的损伤，改善营养状况，提高免疫功能，而肠内营养及混合营养在体液免疫方而优于肠外营养支持。

Comparison of effects of enteral nutrition with parenteral nutrition in critically ill patients

Objective To compare the effect of enteral nutrition with parenteral nutrition in critically ill patients. Methods All of l l2 cases with critically ill were divided into EN group, PN group, mixotrophism group according to modes of tuttrition. Selected 30 cases only oral feeding as control group. Liver function, renal function, TP, Albumin, Hb, TCL, CD4, CD4/CI）8 were compared betfore and l0 days after treatment. Results TP, Albumin, prealbumin, Hb, TCL, CD4, CD4/CD8 of EN group, PN group and mixotrophism group had significant difference before and after treat ment （P 〈 0.05）. lgG of EN group and mixotrophism group had significant difference before and after treatment （P 〈 0.05）, which were higher than PN group and control group （P 〈 0.05）. Conclusion Early nutrition support for critically ill patienls prevent damage of important organs, improve nutriture and immunologic function. EN and mixotrophism may improve humoral immunity more than PN.