| 六味补血颗粒的喷雾制粒工艺研究 |
| |
| 引用本文： | 李剑欣,张曦,魏桂蓉. 六味补血颗粒的喷雾制粒工艺研究[J]. 中南药学, 2011, 9(11): 841-844. DOI: 10.3969/j.issn.1672-2981.2011.11.014 |
| |
| 作者姓名： | 李剑欣 张曦 魏桂蓉 |
| |
| 作者单位： | 湖南省娄底市中心医院药剂科,湖南娄底,417000 |
| |
| 摘 要： | 目的优化六味补血颗粒的喷雾制粒工艺。方法 应用正交试验法,采用喷雾干燥制粒机制粒并在流化床上进行干燥,以浸膏浓缩的相对密度、物料干燥温度及雾化压力为考察因素,以颗粒成品收得率及芍药苷转移率为评价指标。结果最佳工艺参数:浸膏相对密度为1.10(80℃),物料干燥温度为95～100℃,雾化压力为0.25MPa。结论该工艺合理、稳定,为工业化生产提供了实验依据。
|
| 关 键 词： | 六味补血颗粒 喷雾制粒 正交试验 |
Spraying granulation technique of Liuwei Buxue Keli |
| |
| LI Jian-xin,ZHANG Xi,WEI Gui-rong. Spraying granulation technique of Liuwei Buxue Keli[J]. Central South Pharmacy, 2011, 9(11): 841-844. DOI: 10.3969/j.issn.1672-2981.2011.11.014 |
| |
| Authors: | LI Jian-xin ZHANG Xi WEI Gui-rong |
| |
| Affiliation: | LI Jian-xin,ZHANG Xi,WEI Gui-rong(Department of Pharmacy,Loudi Central Hospital,Loudi Hunan 417000) |
| |
| Abstract: | Objective To optimize the condition of the spray granlulation of Liuwei Buxue Keli. Methods The process was studied by orthogonal experimental design,newly-fluid-bed-spray-deier-granulation technique was adopted,and relative density of the fluid extracts,drying temperature and spray pressure were used as inspecting factors,end-product and the transferring rate of paeoniflorin were used as inspecting markers. Results The optimum spraying granulation technique of Liuwei Buxue Keli was as follows:the relative ... |
| |
| Keywords: | Liuwei Buxue Keli spraying granulation orthogonal experiment |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
