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Control of exogenous factors affecting plasma homovanillic acid concentration |
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| Authors: | Michael Davidson Anne B. Giordano Richard C. Mohs Victoria V. Mykytyn Shari Platt Zahra S. Aryan Kenneth L. Davis |
| Affiliation: | 1 Michael Davidson, M.D., is Assistant Professor of Psychiatry at the Mount Sinai School of Medicine in New York City, U.S.A 2 Anne B. Giordani, Ph.D., is Assistant Professor of Psychiatry at the Mount Sinai School of Medicine in New York City, U.S.A 3 Richard C. Mohs, Ph.D., is Associate Professor of Psychiatry at the Mount Sinai School of Medicine in New York City, U.S.A 4 Victoria V. Mykytyn, B.S., is Research Associate at the Mount Sinai School of Medicine in New York City, U.S.A 5 Shari Platt, M.S., is Research Associate at the Mount Sinai School of Medicine in New York City, U.S.A 6 Zahra S. Aryan, M.S., is Research Associate at the Mount Sinai School of Medicine in New York City, U.S.A 7 Kenneth L. Davis, M.D., is Professor of Psychiatry and Pharmacology at the Mount Sinai School of Medicine in New York City, U.S.A |
| Abstract: | Measurements of plasma homovanillic acid (pHVA) concentrations appear to be a valid research strategy in psychiatric disorders in which a central dopamine (DA) abnormality has been implicated. This study provides guidance about the control of some of the exogenous factors affecting pHVA concentrations. Fasting for 14 hours eliminates the dietary effects on pHVA in healthy human subjects. Changing position, walking for 30 minutes, or smoking two cigarettes has no effect on pHVA concentrations. |
| Keywords: | Homovanillic acid diet physical activity smoking |
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