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阿尔茨海默病与氧化应激
引用本文:于德红,魏朝良,包永明,安利佳. 阿尔茨海默病与氧化应激[J]. 生物医学工程学杂志, 2006, 23(5): 1142-1144,1148
作者姓名:于德红  魏朝良  包永明  安利佳
作者单位:大连理工大学,环境与生命学院,大连,116024
摘    要:
随着世界人口的老龄化,阿尔茨海默病(AD)已成为当前研究的热点之一,但目前其确切的发病机制还不完全清楚。本文主要针对AD中出现的氧化应激介体,阐明氧化应激在AD病理过程中可能的致病作用,并提出利用抗氧化途径来预防和治疗AD的可行性策略。

关 键 词:活性氧  阿尔茨海默病(AD)  发病机制  氧化应激
收稿时间:2004-04-05
修稿时间:2004-04-052004-09-15

Alzheimer''''s Disease and Oxidative Stress
Yu Dehong,Wei Chaoliang,Bao Yongming,An Lijia. Alzheimer''''s Disease and Oxidative Stress[J]. Journal of biomedical engineering, 2006, 23(5): 1142-1144,1148
Authors:Yu Dehong  Wei Chaoliang  Bao Yongming  An Lijia
Affiliation:Department of Environment and Life, Dalian University of Technology, Dalian 116024,China
Abstract:
Alzheimer's disease(AD) has abstracted many scientists' interests with the aging of people in the world,but its mechanisms are still remaining unclear.This review will focus on some of the mediators of oxidative stress occurring in AD pathology and their possible role in the AD pathogenesis.Meanwhile,antioxidant approaches for the prevention and treatment of AD are discussed.
Keywords:Reactive oxygen species(ROS) Alzheimer's disease (AD) Pathogenesis Oxidative stress  
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