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A case study: neuroleptic malignant syndrome with risperidone and CYP2D6 gene variation
Authors:Ochi Shinichiro  Kawasoe Koichiro  Abe Masao  Fukuhara Ryuji  Sonobe Kantaro  Kawabe Kentaro  Ueno Shu-ichi
Affiliation:aDepartment of Neuropsychiatry, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan
Abstract:
We present a schizophrenic patient who experienced neuroleptic malignant syndrome with risperidone treatment due to variants of the CYP2D6 gene with reduced function. Clinicians need to be aware of this potential complication.
Keywords:Neuroleptic malignant syndrome   Risperidone   Schizophrenia   CYP2D6 variant
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