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A manic episode in a 64-year-old man: an adverse effect of varenicline
Authors:Ahmed Amir I A
Affiliation:
  • Department of Elderly, Vincent van Gogh Institute, RCG-Venlo, 5912 BL Venlo, The Netherlands
  • Department of Clinical Pharmacology and Toxicology, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands
  • Abstract:
    Varenicline is a novel treatment for smoking cessation. However, it has not been well studied in patients with medical and psychiatric comorbidity. We report a case of an acute manic episode in a 64-year-old man with a history of bipolar disorder post stroke, who was started on varenicline. This case demonstrates the importance of monitoring neuropsychiatric adverse drug reactions after the start of varenicline therapy in patients with a current or past history of mental illness.
    Keywords:Bipolar disorder   Mania   Smoking cessation   Varenicline   Adverse drug reactions   Neuropsychiatric symptoms
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