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纳洛酮抢救地西泮急性中毒
引用本文:丁勇. 纳洛酮抢救地西泮急性中毒[J]. 中国新药与临床杂志, 1997, 0(1)
作者姓名:丁勇
作者单位:丰县人民医院
摘    要:
目的:观察纳洛酮抢救地西泮急性中毒的疗效。方法:33例地西泮急性中毒病人(男性4例,女性29例;年龄22±s8a),在常规疗法基础上,静脉注射(静注)纳洛酮0.4~2.0mg,必要时2h后重复静注;另有对照组41例(男性5例,女性36例;年龄24±8a),仅用洗胃、输液等常规处理。结果:纳洛酮组在清醒时间、住院天数(P<0.01)和转归(P<0.05)等方面疗效优于对照组,纳洛酮组无明显不良反应。结论:纳洛酮抢救地西泮急性中毒病人疗效显著而又安全。

关 键 词:纳洛酮;地西泮;中毒;昏迷

Naloxone in treating acute diazepam poisoning
DING Yong. Naloxone in treating acute diazepam poisoning[J]. Chinese Journal of New Drugs and Clinical Remedies, 1997, 0(1)
Authors:DING Yong
Abstract:
AIM: To observe the effects of naloxone in treating acute diazepam poisoning. METHODS: Thirty-three patients (M 4, F 29; age 22±s 8 a) with acute diazepam poisoning were treated with naloxone 0.4-2.0 mg, iv, in addition to conventional therapy(gastric lavage, infusion etc), and repeated iv after 2 h if necessary. Other 41 patients served as control (M 5, F 36; age 24± 8 a)were treated with the conventional therapy only. RESULTS: In comparison with the control, naloxone showed better effects in consciousness, time of hospitalization (P<0.01), and recoveries (P<0.05). Adverse reactions of naloxone were mild. CONCLUSION: The effects of naloxone in treating acute diazepam poisoning are notable and safe.
Keywords:naloxone  diazepam  poisoning  coma
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