重症手足口病并脑干脑炎的MRI表现及临床特征

目的 探讨重症手足口病并脑干脑炎的MRI表现及临床特征.方法 收集2010年3-5月确诊为手足口病并脑干脑炎的患儿29例,对其MRI与临床资料进行回顾性分析.结果 29例患儿MRI表现:阴性25例,阳性4例,病灶均局限在脑桥和延脑交界部,2例病灶为脑桥、延脑交界处对称性向两侧延伸,2例病灶非对称性向两侧延伸.信号特征均呈斑片状T1加权像(T1WI)略低信号、T2加权像(T2WI)略高信号,边界不清.随访10 d～2个月,脑桥和延脑交界部病灶逐渐变小,长T1、长T2信号改变更显著,边界逐渐清晰.临床特征:29例患儿均有发热和皮疹;神经系统症状中,肢体震颤29例(100%),眼球运动异常(游动或上翻)23例(79.3%),烦躁和惊恐16例(55.2%),行走不稳12例(41.4%);MRI阳性4例患儿有神经系统后遗症,25例阴性患儿无神经系统后遗症.结论 重症手足口病并脑干脑炎的MRI与临床表现具有一定关系,MRI能真实显示其脑干脑炎脑部受损情况及病变发展变化,能为临床诊断、治疗及预后提供可靠的影像学依据.

Magnetic Resonance Imaging and Clinical Features of Severe Hand-Foot-Mouth Disease Complicated with Brainstem Encephalitis

Objective To explore the magnetic resonance imaging(MRI) and clinical features of severe hand-foot-mouth disease(HFMD) complicated with brainstem encephalitis.MethodsThe clinical data of 29 children diagnosed as HFMD complicated with brainstem encephalitis from Mar.to May 2010 were collected.The MRI and clinical data were retrospectively analyzed.ResultsMRI showed that 25 cases were negative,but 4 cases were positive.The lesions in 4 positive cases were located in the junction of the pons and medulla oblong...