LASEK治疗近视眼的临床观察

目的评价准分子激光角膜上皮瓣下磨镶术（Laser epithelial keratomileusis,LASEK）治疗近视眼的安全性和有效性。方法应用LASEK治疗近视眼139例（271眼）,分别观察术后第1,3,7天,1个月、3个月、6个月、1年的眼部症状、屈光状态、视力、眼压、角膜曲率、角膜并发症等情况。结果接受LASEK手术的139例（271眼）在术后1～2 d内均有不同程度的异物感、畏光、流泪等不适症状,角膜上皮水肿,3～7 d后消失。术后1个月屈光状态与术前的屈光度、术后Haze密切相关,多数病例术后7～10 d裸眼视力达到或接近术前矫正视力,术后1年99.3%的病例视力达到或超过术前最佳矫正视力,83%的病例术后裸眼视力≥1.0,33.2%的病例术后裸眼视力高于术前最佳矫正视力。部分病例术后发生的Haze随时间的延长逐渐消退或明显减轻。非接触式眼压计测量术后眼压（9.67±0.42）mm Hg（1 mm Hg=0.133 kPa）。术后角膜曲率（38.47±2.33）较术前（44.05±1.21）明显减小（P〈0.01）,未发现圆锥角膜病例,术中11眼剥离角膜上皮瓣困难,6眼改行PRK,5眼2个月后再次行LASEK。结论 LASEK治疗近视眼适应证宽,尤其适用于角膜厚度较薄、曲率较大的病例,避免了相关的并发症,安全有效。

Clinical Observation of Effects of Laser Epithelial Keratomileusis on Myopia

Objective To evaluate the safety and efficacy of laser epithelial keratomileusis(LASEK) for myopia.Methods Two hundred and seventy one eyes of 139 patients underwent LASEK to correct myopia.The symptoms such as intraocular pressure,corneal complication,diopter and vision were observed on 1 day,3 days,7 days,1 month,3 months,6 months and 1 year after operations.Results After one to two days of operation,139 patients(271 eyes) suffered from paraesthesia,photophobia,and lachrymation and epithelium sheet edema ...