大脑中动脉狭窄所致脑梗死的研究

目的 探讨大脑中动脉(MCA)狭窄所致缺血性脑梗死的机制。方法 对16例MCA狭窄所致的急性闭塞性脑中风患者,应用经颅多谱勒超声(TCD)进行微栓子(MES)检测。结果 16例患者中,14例患者有中度MCA死(CI)6例;而深穿支动脉梗死(PAI)8例,为单发梗死。栓子检测结果：16例病人中,有4例(25％)MES,其中重度狭窄的2例患者均发现MES。结论 栓塞是大脑中动脉狭窄所致急性缺性脑中风的发病机制。交界区多发梗死多由于该区域血流灌注不足导致栓子清除能力的下降引起。狭窄的严重程度可能与栓子的发生密切相关。

STUDY ON THE ISCHEMIC CEREBRAL INFARCTION CAUSED BY MIDDLE CEREBRAL ARTERIAL STENOSIS

Objective To explore the mechanism of ischemic cerebral infarction caused by middle cerebral arterial stenosis. Methods 16 cases of acute obliterative cerebral apoplexy caused by middle cerebral arterial stenosis underwent microembolus detection through transcranial Doppler ultrasonic examination. Results 14 cases were found to have moderate middle cerebral arterial infarction and six of them died. 8 cases died of branch arterial infarction,a kind of solitary infarction. The results of microembolus detection were as follows:4 cases (25% ) were found to have microemboli; 2 cases of severe stenosis were both found to have microemboli. Conclusion The mechanism of acute ischemic cerebral apoplexy caused by middle cerebral arterial stenosis was embolism. The junctional multiple infarctions were mainly caused by insufficient blood flow perfusion, which reduces the ability to clear microemboli. The severity may be closely related to the occurrences of microemboli.