三维适形放疗后程补量照射治疗体部恶性肿瘤的临床研究

目的：探讨三维适形放疗后程补量照射对体部恶性肿瘤的治疗价值。方法：选择体部恶性肿瘤患者180例，先行常规外照射DT 40～50 Gy（20～25 F/4～5 W），再行三维适形放射治疗后程补量照射治疗，放射源为直线加速器15 MVX射线，利用多叶光栅实现4～6个三维适形照射野，分次治疗方法为DT 4～6 Gy/F，隔日1次，4～6次为1疗程，平均补量为DT 30 Gy（24～36 Gy）。结果：治疗后3～6个月，CT及MRI复查显示：134例原发癌中118例肿瘤缩小或消失（占88%）、46例转移癌中38例肿块明显缩小（占83%）；160例患者KPS评分均有提高（占89%）；全部病例未出现明显放疗并发症。结论：三维适形放射治疗体部恶性肿瘤疗效肯定，其后程补量结合常规放疗对于改善患者预后是有益的。

Clinical study on late course 3 dimensional conformal radiation therapy for patients of bodily malignant neoplasms

Objective：To explore the therapeutic value of late course 3 dimensional conformal radiation therapy in the treatment of bodily malignant neoplasms.Methods： One hundred and eighty patients with bodily malignant neoplasms including 46 of 180 patients with metastases tumor were chosen to study. All patents were undertaken late course 3 dimensional conformal radiation therapies after the routine radio therapy. The stereotactic mean radio dose was 30Gy. All patients followed up 3 to 12 months.Results： After the 3 dimensional conformal radiation therapy 3-6 months, 118 in 134 patients primary tumor were reduced, 38in 46 patients metastases tumor were reduced. KPS was improved in 160 of 180 patients. All patients had no radiogical complication.Conclusion： The 3 dimensional conformal radiation therapy for bodily malignant neoplasms were effective, late 3 dimensional conformal radiation therapy combination general radiotherapy were effective in improving prognosis with patients.