不同浓度罗哌卡因用于肌间沟臂丛阻滞的临床对比研究

目的：观察3种浓度罗哌卡因肌间沟臂丛阻滞的效果和不良反应。方法：84例择期行上肢手术患者，随机分为A、B、C、D4组，每组21例。分别采用0．25％、0．375％、0．5％浓度罗派卡因和0．25％布比卡因行肌间沟臂丛神经阻滞。观察感觉神经、运动阻滞时间及阻滞程度、镇痛持续时间、不良反应。结果：B、C组感觉神经阻滞、运动阻滞和镇痛持续时间明显较A组延长（P〈0．05），B、C组运动阻滞程度明显较A组增强（P〈0．01）。结论：3种浓度罗哌卡因肌间沟臂丛阻滞均可满足手术要求，但0．375％罗派卡因更适合于肌间沟臂丛阻滞。

Clinical observation on interscalene brachial plexus block with ropivacaine of three concentrations

Objective:To observe the efficacy and adverse reaction of interscalene brachial plexus block with ropivacaine of three concentrations.Methods: Eighty-four patients undergoing upper limb surgery were randomly divided into 4 groups: Patients in A,B,C and C groups were received the interscalene brachial plexus block with 0.25%,0.375%,0.5% ropivacaine and 0.25% bupivacaine repectively.The onset time of sensory and motor block,the degree of motor block,and analgesia maintenance time were recorded.Results: The onset time of sensory and motor block and analgesia maintenance time were significantly longer in group B and C than those in group A(P<0.05),and the degree of motor block was significantly increased in group B and C compared with group A(P<0.01).Conclusion: 0.375% ropivacaine is more suitable for the interscalene brachial plexus block.