灸法防治肿瘤患者化疗不良反应的文献计量学分析

目的 运用可视化分析法,总结灸法在化疗相关不良反应中的应用规律及发展现状,为灸法在化疗不良反应中的临床应用提供依据。方法 检索自建库至2021年7月8日公开发表在中国知网、万方、生物医学、维普4大数据库的文献,使用Excel对穴位选择、灸法、灸次、治疗周期,治疗时机、温度控制、文献主题等文献基本信息及主要信息进行数据提取。运用Excel和CiteSpace对年分布趋势、研究热点、作者及机构间合作情况进行可视化分析。结果 纳入文献215篇,研究热点共有7个,分别为综述、恶心呕吐、骨髓抑制、白细胞减少、胃肠道反应、乳腺癌、隔姜灸;灸法在化疗后不良反应中的应用有6种,分别为胃肠道不良反应、白细胞减少、骨髓抑制、腹泻、癌因性疲乏、便秘;灸法有7种,穴位有21个;灸法在化疗相关不良反应中的应用年发文量呈递增趋势。结论 灸法能有效改善化疗相关不良反应,但在标准化方案及研究设计规范等方面仍值得进一步研究。

Effect of Moxibustion on Chemotherapy-related Adverse Reaction of Cancer Patients: A Bibliometric Analysis

Objective To summarize the application effect and development of moxibustion in chemotherapy-related adverse reactions with visualization analysis. Methods We searched literature in CNKI, Wanfang, China biomedical database and Weipu, from the inception to July 8, 2021 and Excel was used for data extraction in terms of acupoint selection, moxibustion, moxibustion, treatment cycle, treatment timing, temperature control, literature topics and other basic information. Annual distribution trend, research hotspot, author and inter-agency cooperation of the literature were analyzed by using Excel and Cite Space. Results A total of 215 articles were included and there were 7 research hotspots including review, nausea and vomiting, bone marrow suppression, leukopenia, gastrointestinal reaction, breast cancer, ginger moxibustion. Moxibustion was majorly used in adverse reactions after chemotherapy such as gastrointestinal adverse reactions, leukopenia, bone marrow suppression, diarrhea, cancer-related fatigue, constipation.There were 7 types of moxibustion and 21 acupoint selection.The number of papers on moxibustion in chemotherapy-related adverse reactions showed an increasing trend. Conclusion Moxibustion can effectively improve the side effects of chemotherapy, but further study is needed on standardized research design and scheme.