老年腔隙性脑梗死患者抑郁情绪及影响因素的研究

脑梗死后抑郁状态是脑卒中常见的并发症之一 ,其发生率为 2 3%～ 6 5 % 1] 。脑梗死后抑郁不仅严重影响患者的生活质量 ,而且可直接影响其康复和预后。随着医学影像学的发展 ,腔隙性脑梗死(Ｌａｃｕｎａｒｃｅｒｅｂｒａｌｉｎｆａｒｃｔｉｏｎ ,ＬＩ)的诊断率逐渐增高。为探讨老年ＬＩ患者抑郁的临床特点 ,我们收集老年ＬＩ病人 12 6例 ,对其抑郁的特点、抑郁症状与ＬＩ的关系及影响因素进行了研究 ,现报告如下。1　资料与方法1.1　研究对象为 1998年 1月至 2 0 0 0年 12月在本院及济宁市一院精神科住院的ＬＩ病人 12 6例 ,年龄 6 0～ 82…

Study on Depression of Senile Lacunar Cerebral Infarction

Objective:To explore the feature of depression in senile patients with Lacunar infarction (LI)and its related factors.Methods:The level of depression of 126 senile LI patients identified by CT or MRI was measured by HAMD.Comparison between 76 cases of depression and 50 cases of nondepression on sites of infarction ,number of infarction,clinical nerve function limitation score(CNS),past history and educational level was analyzed.Results:Among 126 senile LI patients ,there were 76 cases(60.3%)with depression;Multiple cerebral infarction,Subcortical cerebral infarction were commonly associated with depression;Patients with multiple and subcortical infarction got significantly higher score of depression than those with single and cortical infarction.Cases with history of hypertension,diabetes, coronary heart disease or low education were more frequently found in the depression group compared with the non depression group.Depression was significantly and positively correlated with CNS.Conclusion:The biological and psychosocial factors can play important roles in depression of senile lacunar infarction.