|
|||||
|
|
Cutaneous vasculitis induced by TNF inhibitors: a report of three cases |
|
| Authors: | Keita Fujikawa Atsushi Kawakami Tomayoshi Hayashi Naoki Iwamoto Shin-ya Kawashiri Toshiyuki Aramaki Kunihiro Ichinose Mami Tamai Kazuhiko Arima Makoto Kamachi Satoshi Yamasaki Hideki Nakamura Hiroaki Ida Tomoki Origuchi Katsumi Eguchi |
| Affiliation: | 1. Unit of Translational Medicine, Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan 2. Department of Pathology, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan 3. Nagasaki University School of Health Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8520, Japan |
| Abstract: | We describe 3 rheumatoid arthritis (RA) patients with anti-tumor necrosis factor (TNF) therapy-induced cutaneous vasculitis. Two cases were induced by infliximab and the other, in whom cutaneous vasculitis was found early at the start of therapy, was induced by etanercept. Skin biopsy was obtained in 2 patients, with histology-proven leukocytoclastic vasculitis. One patient spontaneously improved after cessation of the TNF inhibitor. Two patients required oral corticosteroid, the efficacy of which was observed to be excellent and rapid. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |