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Y microdeletions in the Istria county, Croatia
Authors:Medica I  Gligorievska N  Prenc M  Peterlin B
Affiliation:Division of Medical Genetics, Department of Obstetrics and Gynecology, University Medical Centre, Ljubljana 1000, Slovenia.
Abstract:
Aim: To establish the frequency of Y chromosome microdeletions in an unselected group of infertile Croatian men. Methods: An unselected group of 105 patients (male partners of infertile couples), both with idiopathic and non-idiopathic infertility, consecutively referred to the outpatient infertility clinic, gynecology department, General Hospital Pula, Istria County, Croatia, was examined for the presence or absence of Y chromosome microdeletions by polymerase chain reaction analysis. Results: One of the 105 men (0.95%, 95% CI = 0.17-5.2%) was found to have a microdeletion. Conclusion: A low frequency of Y chromosome microdeletions was found in the group of unselected infertile Croatian men.
Keywords:male infertility    Y chromosome    AZF region    microdeletion
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