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DNA neosynthesis in Auerbach plexus ganglia isolated from the rat hypertrophic gut: An electrophoretic analysis |
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| Authors: | Maria G. Giacobini Robecchi Paolo Borrione Marco Canavese Stefano Guena Adriana Paraninfo Alessandro Poncino Lorenzo Silenco |
| Affiliation: | aDipartimento di Anatomia e Fisiologia Umana, Sezione di Neuroanatomia e Neuroembriologia, Universita' degli Studi di Torino, C. so M. D'Azeglio 52, 10126 Torino, Italy;bDipartimento di Genetica, Biologia e Chimica Medica, Universita' degli Studi di Torino, Torino, Italy |
| Abstract: | We analysed using electrophoresis the total genomic DNA extracted from isolated Auerbach plexus ganglia of the hypertrophic duodenum upstream from a partial experimental stenosis. Results indicated the presence of two extra-bands migrating below the high molecular weight DNA, suggesting that DNA amplification is the basic mechanism of the DNA neosynthesis previously observed in myenteric neurons. |
| Keywords: | neuroplasticity DNA amplification Auerbach plexus ganglia rat hypertrophic gut |
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