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| 尿素乳酸软膏治疗手足皲裂症临床研究 | |
| 引用本文： | 汪科,季素珍,陈喜雪,关欣,朱学骏. 尿素乳酸软膏治疗手足皲裂症临床研究[J]. 中国药物应用与监测, 2004, 1(3): 4-6 |
| 作者姓名： | 汪科 季素珍 陈喜雪 关欣 朱学骏 |
| 作者单位： | 北京大学第一医院皮肤性病科,北京,100034 |
| 摘 要： | 目的:评价尿素乳酸软膏(商品名"干芙美")治疗手足皲裂症的疗效和安全性。方法:采用随机双盲、安慰剂对照研究,试验组和对照组均为局部用药,2次/d,疗程4周。结果:共入组手足皲裂患者26例,包括试验组和对照组各13例。治疗4周后,试验组的总有效率为100％,而对照组的总有效率为61.6％。两组之间的有效率比较,具有统计学意义(P<0.01)。试验组有1例发生不良事件。结论:尿素乳酸软膏治疗手足皲裂症具有很高的疗效,且安全性和耐受性良好,使用方便。 |
| 关 键 词： | 手足皲裂症 尿素乳酸软膏 |
| 文章编号： | 1672-8157(2004)03-0004-03 |
| 修稿时间： | 2004-06-23 |
A clinical trial of urea & lactic acid compound ointment for the treatment of rhagadia manus et pedis |
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| WANG Ke,JI Su-zhen,CHEN Xi-xue,et al. A clinical trial of urea & lactic acid compound ointment for the treatment of rhagadia manus et pedis[J]. , 2004, 1(3): 4-6 | |
| Authors: | WANG Ke JI Su-zhen CHEN Xi-xue et al |
| Abstract: | Objective:To evaluate the efficacy and safety of urea & lactic acid compound ointment for the treatment of rhagadia manus et pedis. Methods: The trail was performed in randomized double-blind and placebo control method.All the subjects were administrated with drugs twice a day for four weeks. Results:The total number of all the subjects was 26, including 13 subjects in trial group and 13 subjects in control group. The total improved rates were 100% in trail group after four-week therapy, while in control group, were 61.6%. The improved rates between two groups had statistic differences (P<0.01).One case of adverse event occured in trail group. Conclusion: The urea & lactic acid compound ointment has good efficacy,safety and tolerability in treatment of rhagadia manus et pedis, and can be used conveniently. |
| Keywords: | Rhagadia manus et pedis Urea & lactic acid compound ointment |
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