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| The Effect of Combining Fast Neutron and Photon Irradiation on the Human Osteosarcoma OS-732 Cell Line | |
| 引用本文： | LinchunFeng LinMa JingxiangHuang DongYang YingxuanWang MingxueSun JinhuaTang WeikeChang ChengxiangLiu. The Effect of Combining Fast Neutron and Photon Irradiation on the Human Osteosarcoma OS-732 Cell Line[J]. 中国肿瘤临床(英文版), 2005, 2(3): 654-657. DOI: 10.1007/BF02739726 |
| 作者姓名： | LinchunFeng LinMa JingxiangHuang DongYang YingxuanWang MingxueSun JinhuaTang WeikeChang ChengxiangLiu |
| 作者单位： | DepartmentofRadiotherapy,GeneralHospitalofPLA,Beijing100853,China |
| 摘 要： | OBJECTIVE To determine the lethal effect of combining fast neutron with photon radiation on the OS-732 cell line. METHODS We examined the effect of irradiation by fast neutrons, photons and a mixed beam (fast neutrons plus photons) on the lethality and colony forming ability of the OS-732 cell line at different times. RESULTS Following a single irradiation close, the lethality was markedly strong at 24, 48 and 72 h in the group treated with fast neutrons alone and in the mixed beam group in which there was a high proportion of fast neutrons. CONCLUSION The lethal effect of a fast neutron and mixed beam with a high proportion of fast neutrons on the OS-732 cell line is highly significant. These studies provide guidance for the clinical application of fast neutrons for osteosarcoma treatment. |
| 关 键 词： | 中子 光子照射 骨肉瘤 OS-732 肿瘤细胞 |
| 收稿时间： | 2004-09-29 |
| 修稿时间： | 2005-04-08 |
The effect of combining fast neutron and photon irradiation on the human osteosarcoma OS-732 cell line |
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| Linchun Feng,Lin Ma,Jingxiang Huang,DONG Yang,Yingxuan Wang,Mingxue Sun,Jinhua Tang,Weike Chang,Chengxiang Liu. The effect of combining fast neutron and photon irradiation on the human osteosarcoma OS-732 cell line[J]. Chinese Journal of Clinical Oncology, 2005, 2(3): 654-657. DOI: 10.1007/BF02739726 | |
| Authors: | Linchun Feng Lin Ma Jingxiang Huang DONG Yang Yingxuan Wang Mingxue Sun Jinhua Tang Weike Chang Chengxiang Liu |
| Affiliation: | Department of Radiotherapy,General Hospital of PLA,Beijing100853,China |
| Abstract: | OBJECTIVE To determine the lethal effect of combining fast neutron with photon radiation on the OS-732 cell line.METHODS We examined the effect of irradiation by fast neutrons, photons and a mixed beam (fast neutrons plus photons) on the lethality and colony forming ability of the OS-732 cell line at different times.RESULTS Following a single irradiation close, the lethality was markedly strong at 24, 48 and 72 h in the group treated with fast neutrons alone and in the mixed beam group in which there was a high proportion of fast neutrons.CONCLUSION The lethal effect of a fast neutron and mixed beam with a high proportion of fast neutrons on the OS-732 cell line is highly significant. These studies provide guidance for the clinical application of fast neutrons for osteosarcoma treatment. |
| Keywords: | human osteosarcoma OS-732 cell line fast neutron photon radiotherapy |
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