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Fox-Fordyce disease: report of two cases with perifollicular xanthomatosis on histological image
Affiliation:1. Dermatopathology Department, Dr. Manuel Gea González General Hospital – Mexico City, Mexico.;2. Internal Medicine, Universidad Nacional Autónoma de México (UNAM) – Mexico City, Mexico.;3. Dermatology Department, Juárez Centro Hospital – Mexico City, Mexico.;4. Clínica Dermatológica Valdés – León, Guanajuato, Mexico.
Abstract:Fox-Fordyce disease is a relatively infrequent pathology of the apocrine glands that affects almost exclusively young women. The disease is characterized by the presence of pruritic follicular papules mainly in the armpits that respond poorly to treatment and severely affect the patient’s quality of life. We report two cases with clinical diagnosis and histopathological confirmation, presenting perifollicular xanthomatosis on histological examination, recently described as a distinctive, consistent, and specific feature of this disease.
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