| 冷水游泳对去肾上腺大鼠下丘脑,垂体和血浆AVP含量的影响 |
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| 引用本文： | 赵小林 宋朝佑. 冷水游泳对去肾上腺大鼠下丘脑,垂体和血浆AVP含量的影响[J]. 放射免疫学杂志, 1998, 11(6): 326-329 |
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| 作者姓名： | 赵小林 宋朝佑 |
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| 作者单位： | 第二军医大学神经生物学教研室!200433 |
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| 摘 要： | ＡＶＰ主要合成于下丘脑的室旁核和视上核，正常情况下，每毫升血浆ＡＶＰ含量在１０ｐｇ以下，近年来的研究表明，疼痛、手术、应激等强刺激可引起ＡＶＰ大量释放，血浆中的ＡＶＰ含量可达１００ｐｇ以上。由于ＡＶＰ可使血管平滑肌收缩，并具ＣＲＦ样作用，可促进垂体释放ＡＣＴＨ，因此被认为是一种应激激素，而下丘脑－垂体－肾上腺皮质轴被认为是经典的应激系统。本工作旨在通过去除应激轴上的肾上腺这一环节，来验证ＡＶＰ是否
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| 关 键 词： | 应激 下丘脑 垂体 血浆 精氨酸加压素 |
EFFECT OF SWIMMING IN COOL WATER ON THE CONTENTS OF ARG-VASOPRESSIN IN HYPOTHALAMUS, PITUITARY AND PLASMA IN RATS AFTER ADRENALECTOMY |
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| Zhao Xiaolin Song Chaoyou Wang Chenghai Lu Changlin. EFFECT OF SWIMMING IN COOL WATER ON THE CONTENTS OF ARG-VASOPRESSIN IN HYPOTHALAMUS, PITUITARY AND PLASMA IN RATS AFTER ADRENALECTOMY[J]. Journal of Radioimmanology, 1998, 11(6): 326-329 |
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| Authors: | Zhao Xiaolin Song Chaoyou Wang Chenghai Lu Changlin |
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| Affiliation: | Zhao Xiaolin Song Chaoyou Wang Chenghai Lu ChanglinDepartment of Neurobiology,Department of Training,Second Military MedicalUniversity Shanghai,200433 |
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| Abstract: | Tn order to investigate the role of vasopressin in stress, we investigated the effect of swimming in cool water on the contents of arg-vasopressin in the hypothalamus, pituitary and plasma of rats after adrenalectomy with RIA. The results showed that the ir-AVPcontents in hypothalamus was significantly increased at 1 and 20 min after swimming in cool water, while AVP content in pituitary was significantly decreased. A slight increase of ir-AVP content in plasma occurred with no statistical significance. However, the level of ir-AVP in plasma was significantly increased when the rats were drowned. The data suggested that AVP played a direct role in the stress reactions althongh it was also involved in stress through activating hypothalamus-pituitary-adrenal axis. |
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| Keywords: | swimming in Cool water Arg-vasopressin Adrenalectomy |
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