| 穿刺活检在诊断肝血管平滑肌脂肪瘤中的价值 |
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| 引用本文： | 刘毅强,孙宇,李忠武,薛卫成,陆爱平,李吉友.穿刺活检在诊断肝血管平滑肌脂肪瘤中的价值[J].诊断病理学杂志,2011,18(1):52-55. |
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| 作者姓名： | 刘毅强 孙宇 李忠武 薛卫成 陆爱平 李吉友 |
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| 作者单位： | 北京大学临床肿瘤学院,北京肿瘤医院暨北京市肿瘤防治研究所病理科,恶性肿瘤发病机制及转化研究教育部重点实验室,北京,100142 |
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| 摘 要： | 目的总结肝血管平滑肌脂肪瘤穿刺活检标本的组织病理学形态、免疫组化及诊断和鉴别诊断要点,探讨提高诊断准确率、降低误诊率的方法。方法对9例肝血管平滑肌脂肪瘤穿刺活检病例进行临床病理与免疫组化观察。结果 9例肝血管平滑肌脂肪瘤中女性8例,男性1例,年龄25～62岁,中位年龄43岁;肿瘤直径2～10 cm;5例为肌瘤型,3例为混合型,1例为脂肪瘤型;其中8例HMB45(+),1例HMB45(-)但melan A(+)。仅1例术前影像学诊断考虑为肝血管平滑肌脂肪瘤,而未行免疫组化检测、仅依靠光镜观察,有4例得出正确的病理诊断。结论肝血管平滑肌脂肪瘤的组织形态变化多样,穿刺活检标本更易误诊或漏诊,确切的病理诊断还需借助于免疫组化,尤其是HMB45和melan A对鉴别诊断有重要意义。
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| 关 键 词： | 肝肿瘤 血管平滑肌脂肪瘤 穿刺活检 免疫组化 |
Values of needle aspiration biopsy in pathologic diagnosis of hepatic angiomyolipoma |
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| LIU Yi-qiang,SUN Yu,LI Zhong-wu,XUE Wei-cheng,LU Ai-ping,LI Ji-you.Values of needle aspiration biopsy in pathologic diagnosis of hepatic angiomyolipoma[J].Chinese Journal of Diagnostic Pathology,2011,18(1):52-55. |
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| Authors: | LIU Yi-qiang SUN Yu LI Zhong-wu XUE Wei-cheng LU Ai-ping LI Ji-you |
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| Institution: | LIU Yi-qiang,SUN Yu,LI Zhong-wu,XUE Wei-cheng,LU Ai-ping,LI Ji-you.(Key laboratory of Carcinogenesis and Translational Research(Ministry of Education),Department of Pathology,Peking University School of Oncology,Beijing Cancer Hospital and Institute,Beijing 100142,China) |
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| Abstract: | Objective To describe the clinicopathologic and immunohistochemical characteristics and differential diagnosis of nine cases of hepatic angiomyolipoma(HAML)examined by needle aspiration biopsy,in purpose to investigate the methodology and to enhance the diagnostic accuracy and lower the misdiagnosis rate.Methods Nine cases of HAML were analyzed using H & E and immunohistochemical stains.Results This group of HAML was composed of 8 females and 1 male,with age ranged 25-65 years(median 43 years).The size of t... |
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| Keywords: | Liver neoplasms Angiomyolipoma Needle aspiration biopsy Immunohistochemistry |
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