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人大肠癌细胞体外常温及温热环境中药物敏感性试验
引用本文:冷静,陈利生.人大肠癌细胞体外常温及温热环境中药物敏感性试验[J].广西医科大学学报,1997,14(2):33-35.
作者姓名:冷静  陈利生
作者单位:广西医科大学微生物学教研室
摘    要:用MTT比色法对20例大肠癌患者术后标本在常温及温热环境中进行体外药物敏感性试验,结果显示,某些药物在温热环境中,对癌细胞的杀伤作用有显著提高,此项试验为临床温热化疗法提供了理论依据。

关 键 词:温热法  药敏实验  大肠肿瘤  四甲基偶氮唑盐

IN VITRO DRUG SENSITIVITY TEST OF HUMAN CARCINOMA CELLS OF LARGE INTESTINE UNDER NORMAL ATMOSPHERIC TEMPERATURE AND HYPERTHERMIC ENVIRONMENT
Abstract:In vitro drug sensitvity tests by MIT chromatometry were performed to examine tumor specimens obtained from 20 patients with carcinoma of large intestine.The tumor cells were exposed to normal atmospheric temperature and hyperthermic environment respectively.The results indicate that hyperthermie environment can enhance the tumorocidal effect of certain drugs(DDP and MMC).This investigation provides theoretical support for the application of hyperthemic chemotherapy.
Keywords:MMT  carcinoma of large intestine  hyperthermia  drug sensitivity test
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