致畸“四项”血清学检测在妇产科的应用

探讨致畸“四项”—弓形虫、巨细胞、风疹、单纯疱疹病毒对孕产妇的影响。随机选择正常妊娠妇女１５０ 例,有异常孕产史妇女２００ 例,采用酶标免疫血清学诊断,进行血清“四项”检测。结果表明：有异常孕产史妇女的“四项”阳性感染率平均高于正常妊娠期妇女,而“两项”阳性或“两项”以上阳性感染有非常显著意义。提示,抓好优生工作必须从孕前、乃至全孕期进行“四项”监控措施,以降低缺陷儿出生的发生率,提高人类健康水平。

Application of Serological Detection of Four Teratogenic items in Gynecology and Obstetrics

To study the influence of four items of teratogen Toxoplasma.Cytomegalovirus.Rubella virus and Herpesvirus on pregnant and puerperant women,150 normal pregnant women and 200 pregnant women with history of abnormal pregnancy were selected for determination of the four items in serum by ELISA.The average infection rates of the four items in pregnant women with abnormal history of pregnancy were higher than those of normal pregnant women,and infection with two or over two items had great significance.The results suggest that measures of monitering the four teratogenic items should be emphasized before and throughout the whole period of pregnancy in order to reduce the incidence of abnormal birth and promote the health of humanity.