Mismatch negativity (MMN), the deviance-elicited auditory deflection, explained |
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| Authors: | Patrick J. C. May Hannu Tiitinen |
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| Affiliation: | Department of Biomedical Engineering and Computational Science, Helsinki University of Technology, Espoo, Finland |
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| Abstract: | The current review constitutes the first comprehensive look at the possibility that the mismatch negativity (MMN, the deflection of the auditory ERP/ERF elicited by stimulus change) might be generated by so-called fresh-afferent neuronal activity. This possibility has been repeatedly ruled out for the past 30 years, with the prevailing theoretical accounts relying on a memory-based explanation instead. We propose that the MMN is, in essence, a latency- and amplitude-modulated expression of the auditory N1 response, generated by fresh-afferent activity of cortical neurons that are under nonuniform levels of adaptation. |
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| Keywords: | Mismatch negativity (MMN) N1 N100 Event-related potential Event-related field Electroencephalography Magnetoencephalography Human Auditory Memory Attention Computational modeling Cortex Adaptation Lateral inhibition |
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