早期无创正压通气治疗在重症肺炎中的观察

目的：探讨早期无创正压通气在重症肺炎中的效果。方法：选取2010年1月～2013年10月我科收治的重症肺炎46例，在常规治疗上，治疗组31例给予早期无创通气，记录二组呼吸频率、心率、PH、PaO2、PaCO2、气管插管率等，作统计学分析。结果：治疗48h后，治疗组呼吸窘迫得到明显缓解，氧分压改善，心率下降，气管插管率降低，有显著差异（P＜0.05）， PH、PaCO2的变化无统计学意义（P＞0.05）。结论：重症肺炎患者早期使用无创正压通气治疗，可以纠正缺氧，改善氧合及自觉症状，一定程度上避免有创通气，从而改善预后。

Observation on early-stage noninvasive positive pressure ventilation for severe pneumonia

Objective： To investigate the efficacy of early-stage noninvasive positive pressurev entilation for severe pneumonia. Methods：46 cases with severe pneumonia in our department from January, 2010 to October,2013 were selected. Besides the routine therapy, the cases in the treatment group were tr eated with ear ly-stage no ninvasive positive pressure v entilation. The resp iratory frequency, heart rate, PH, PaO2,PaCO2, therate of endotr acheal intubation of th e groups were recorded and an alyzed. Results：After 48h, respiratory distress in the was obviously relieved, ox ygen partial pressure was improved, heart ra te was reduced and tracheal intub ation rate was decreased with s ignificant difference （P〈 0.05）, but the changes of PH,PaCO2 had no statistica l significance （P〉0.05）. Conclusion：The patients with severe pneumonia treated with early-stage noninvasive positive pressure ventilation can improve oxygenation and symptoms. To some extent, this treatment avoids invasive mechanical ventilation and improves the prognosis.