即时检测全血降钙素原在急诊感染患者的应用价值

目的 评估即时检测（POCT）全血降钙素原（PCT）应用于急诊临床的可行性。方法 采用POCT法对疑诊感染患者的全血标本进行PCT测定,将结果与中心实验室检测结果进行对比。结果 与中心实验室相比,POCT法显著缩短了临床周转时间（TAT）。通过kappa检验对两种方法获得的结果进行一致性分析,结果 表明,以0.5 ng/mL和2ng/mL为临界点,kappa系数分别为0.786和0.923,两种检测方法所得结果一致性较好。结论 POCT法检测PCT快速可靠,适用于急诊临床工作。

Application of point-of-care testing for procalcitonin in emergency clinical work

Objective The feasibility of point-of-care testing（POCT） for procalcitonin （PCT）in emergency clinical work was assessed. Methods PCT determination of whole blood samples from patients with suspected infection was implemented by POCT. The results from POCT were compared with that from a central laboratory. Results The clinical Turn-around Time （TAT） of PCT determination were significantly shortened by POCT. Consistency analysis of the results obtained by the two methods was carried out by kappa test. With 0.5 ng/mL and 2 ng/mL: as the critical points, the kappa coefficients are 0.786 and 0.923, and the results obtained by the two detection methods are highly consistent. Conclusion Determination of PCT by POCT is fast and reliable and it is suitable for emergency clinical work.