Confocal Laser Scanning Microscopy Analysis of 10 Cases of Craniofacial Fibrous Dysplasia |
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| Authors: | Luigi Laino Gianfranco Favia Dardo Menditti Francesco De Francesco Carmen Salerno Michele Scivetti |
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| Affiliation: | 1. Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy,;2. Dental Clinic, University of Bari, Bari, Italy,;3. Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, Second University of Naples, Naples, Italy, and;4. Department of Head and Neck and Plastic-Reconstructive Sciences, Second University of Naples, Naples, Italy |
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| Abstract: | Fibro-osseous lesions (FOL) represent a heterogeneous group of lesions that exhibit a variety of clinic-pathological features. Recently, based on the new World Health Organization classification system, these lesions were reclassified as follows: (1) fibrous dysplasia (FD), (2) osseous dysplasia, and (3) ossifying fibroma. Nevertheless, the nosologic placement of FOL may be problematic because of substantial overlap in the histopathological findings. In this study, we analyzed 10 cases of FD by both optical and confocal laser scanning microscopy, a research technique based on the laser light microscopic analysis of stained biological samples that allows improved tissue imaging and bidimensional pictures with high resolution at the cellular level to provide a better understanding of the diagnosis of this disease. |
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| Keywords: | Autofluorescence confocal laser scanning microscopy fibrous dysplasia |
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