25例脊髓动静脉畸形治疗

目的　探讨脊髓髓内动静脉畸形的栓塞方法。方法　 2 5例脊髓髓内血管畸形患者 ,均行血管内栓塞治疗 ,早期 4例在肋间动脉或腰动脉直接注射硬脑膜颗粒或PVA等 ,近期 9例将微导管插至供血动脉远端以PVA栓塞 ,1例先以NBCA栓塞供血动脉上的动脉瘤 ,再以Embosphere栓塞AVM。 7例以NBCA栓塞。 5例直接手术切除病灶 ,2例栓塞联合手术治疗。结果　 2 0例栓塞后造影证实 12例几乎完全栓塞 ,8例为大部分栓塞 ,经半年～ 2年随访 ,16例临床症状均有不同程度改善 ,4例临床症状无明显变化 ,均未出现出血症状。结论　对于髓内幼稚型和不能手术的团块型AVM ,血管内栓塞治疗为首选治疗。

Treatment of spinal intramedullary arteriovenous malformations in 25 patients

Objective To evaluate the efficacy of embolization for spinal intramedullary arteriovenous malformations.Methods 25 patients with spinal intramedullary arteriovenous malformations (AVMs) were reviewed. Embolic therapy was conducted in 4 patients by introducing the tip of a catheter into the segmental arteries and injecting lyophilized dura or polyvinyl alcohol(PVA). Microcatheter were navigated into the feeding arteries and injected PVA in 9 patients, and NBCA in 7 patients. Embosphere was used after embolizing an aneurysm in the feeding artery with NBCA in one pateint. Results Spinal angiography immediately after embolization disclosed that the lesion were obliterated almost entirely in 12 cases and partially in others. The anterior or posterior spinal artery was preserved in all patients recently. The clinical follow-up period after embolization ranged from 6 to 60 months. 16 patients improved but four patients did not show any improvement.Conclusions Embolization appears to be the treatment of first choice in the management of juvenile or partial glomus AVMs which are not amenable to surgery.