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抑郁症的睡眠脑电图与人脑兴奋守恒假说
引用本文:喻东山,张心保,侯钢,徐捷,孙旦晖,耿直.抑郁症的睡眠脑电图与人脑兴奋守恒假说[J].神经疾病与精神卫生,2004,4(1):13-14.
作者姓名:喻东山  张心保  侯钢  徐捷  孙旦晖  耿直
作者单位:210029,南京医科大学附属脑科医院
基金项目:南京市跨世纪学科带头人后备人员专项基金资助项目(2 0 0 2 80 55)
摘    要:目的 探索抑郁症状与睡眠脑电图参数的相关性。方法 对 18例抑郁症和 10例正常人评定汉密尔顿抑郁评定量表 (HAMD)和检测睡眠脑电图。结果 HAMD总分与觉醒次数及REM密度分别呈显著正相关 (r分别等于 0 .4 0 8和 0 .4 4 5 ,P均 <0 .0 5 )。结论 抑郁症和正常人的白天中枢抑制与夜间中枢兴奋相关 ,从而支持人脑兴奋守恒假说。

关 键 词:抑郁症  睡眠  脑电图  人脑兴奋守恒假说  诊断
文章编号:1009-6574(2004)01-0013-02
修稿时间:2003年12月14

Sleep Electroencephalogram (EEG) in Depression and Exciting Constant in Human Brain
Yu Dongshan,Zhang Xinbao,Hou Gang,et al..Sleep Electroencephalogram (EEG) in Depression and Exciting Constant in Human Brain[J].Nervous Diseases and Mental Health,2004,4(1):13-14.
Authors:Yu Dongshan  Zhang Xinbao  Hou Gang  
Abstract:Objective To explore the correlations between depressive symptoms and parameters of Sleep EEG. Methods It was estimated for Hamilton Depressive Rating Scale (HAMD) and the parameters of Sleep EEG in 18 patients with depression and 10 normal controls. Results There was a significant positive correlation between total score (HAMD) and Awaking Time(r=0.408,df=26,P< 0.05). There was a significant positive correlation between total score of HAMD and Rapid Eye Move (REM) sleep. Conclusions There was a correlation between Central Nervous System (CNS) inhibition on day and CNS excitation at night in depression and normal controls, which supported the hypothesis of exciting constant in human brain.
Keywords:Depression  Sleep electroencephalogram  Excitation  Constant
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