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The efficacy of substances with antihypoxic action in experimental hyperlipidemia] |
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| Authors: | V E Ryzhenkov O V Remezova V F Triufanov L E Vasil'eva |
| Abstract: | Experiments on rats, guinea pigs and rabbits with hyperlipidemia induced by high-cholesterol diet have revealed that the specific antihypoxic drug oliphen has hypolipidemic effect which is least pronounced in oral GABA. Oliphen causes a significant increase in alpha-cholesterol (antiatherogenic lipoprotein cholesterol) decreased by hyperlipidemia. It is suggested that oliphen improves hepatic receptor-dependent uptake and atherogenic lipoprotein degradation. |
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