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Antimicrobial constituents of Foeniculum vulgare
Authors:Kwon Yong Soo  Choi Won Gyu  Kim Won Jun  Kim Woo Kyung  Kim Myong Jo  Kang Won Hee  Kim Chang Min
Affiliation:College of Pharmacy, Kangwon National University, Chuncheon, Korea.
Abstract:
A phenyl propanoid derivative, dillapional(1) was found to be a antimicrobial principle of the stems of Foeniculum vulgare (Umbelliferae) with MIC values of 125, 250 and 125/ against Bacillus subtilis, Aspergillus niger and Cladosporium cladosporioides, respectively. A coumarin derivative, scopoletin(2) was also isolated as marginally antimicrobial agent along with inactive compounds, dillapiol(3), bergapten(4), imperatorin(5) and psolaren(6) from this plant. The isolates 1-6 were not active against the Escherichia coli.
Keywords:Foeniculum vulgare   Dillapional  Scopoletin  Dillapiol  Bergapten  Imperatorin  Psolaren  Antimicrobial activity
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