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微血管病变与缺血性心脏病
引用本文:田骆冰,夏岳,刘超,刘坤申. 微血管病变与缺血性心脏病[J]. 心血管病学进展, 2009, 30(6)
作者姓名:田骆冰  夏岳  刘超  刘坤申
作者单位:河北医科大学第一医院心内科,河北,石家庄,050031
摘    要:冠状动脉微血管在心肌的血供中起着重要作用,冠状动脉微循环对冠心病的发生、发展、疗效及预后具有重要影响而备受人们重视。目前冠状动脉微血管病变主要分为X综合征和冠脉内慢血流现象,二者都与缺血性心脏病存在着密切的关系,但发病机制有所不同。X综合征主要是冠状动脉微血管痉挛所致,而冠脉内慢血流现象传统上被认为与微血管功能失调有关。此外慢血流现象可能是缺血性心脏病的一种新的发病机制,它可能代表了动脉粥样硬化和内皮功能失调的早期阶段。并且二者在治疗上有所不同。

关 键 词:微血管病变  缺血性心脏病  X心脏综合  慢血流现象

Microvascular Disease and Ischemic Heart Disease
TIAN Luo-bing,XIA Yue,LIU Chao,LIU Kun-shen. Microvascular Disease and Ischemic Heart Disease[J]. Advances in Cardiovascular Diseases, 2009, 30(6)
Authors:TIAN Luo-bing  XIA Yue  LIU Chao  LIU Kun-shen
Affiliation:TIAN Luo-bing; XIA Yue; LIU Chao; LIU Kun-shen(Cardiac Department; The First Hospital of Hebei Medical University; Shijiazhuang; 050031; China);
Abstract:Small coronary arteries play an important role in the blood supply of the myocardial tissues. Microcirculation has an important effect on the pathogenesis, development, therapy, and prognosis of coronary artery disease. At present, coronary microvascular disease mainly includes syndrome X and coronary slow flow phenomenon, which is closely related to ischemic heart disease. However, their pathogenesis differs;syndrome X is caused by a spasm of the microvessels, while coronary slow flow phenomenon is related to a microvascular disfunction. Coronary slow flow phenomenon may be a new pathogenic mechanism for ischemic heart disease.
Keywords:microvascular disease  syndrome X  ischemia heart disease  slow flow phenomenon
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