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阿扎司琼联合地塞米松预防腹腔镜胆囊切除恶心呕吐的疗效观察
引用本文:于带弟.阿扎司琼联合地塞米松预防腹腔镜胆囊切除恶心呕吐的疗效观察[J].现代医药卫生,2011,27(11):1617-1618.
作者姓名:于带弟
作者单位:祁阳县人民医院,湖南,祁阳,426100
摘    要:目的:观察阿扎司琼联合地塞米松对预防腹腔镜胆囊切除术后恶心呕吐(post-operative nausea and vomiting,PONV)的疗效.方法:选择腹腔镜胆囊切除手术患者80例,随机分为4组,每组20例.A组:麻醉诱导前静脉注射生理盐水2 mL,手术缝皮时静脉注射阿扎司琼10 mg,B组:麻醉诱导前静脉注射地塞米松10 mg,手术缝皮时静脉注射生理盐水2 mL;C组:麻醉诱导前静脉注射地塞米松10 mg,手术缝皮时给予阿扎司琼10 mg;D组:麻醉诱导前和手术缝皮时均给予生理盐水4 mL.观察并记录四组患者术后24小时恶心呕吐发生的例数、程度与不良反应.结果:术后24小时内,A、B、C三组恶心呕吐发生率较D组低,差异有统计学意义(P<0.05),A B两组问的恶心呕吐发生率差异无显著性(P>0.05),C组术后恶心呕吐发生率较A、B两组低,差异有显著性(P<0.05).结论:阿扎司琼联合地塞米松能有效预防腹腔镜胆囊切除术患者术后恶心呕吐,效果较单用阿扎司琼或地塞米松更佳.

关 键 词:阿扎司琼  地塞米松  腹腔镜  恶心呕吐

Azasetron combined with dexamethasion in prevention of nausea and vomiting after laparoscopic cholecystectomy
YU Dai-di.Azasetron combined with dexamethasion in prevention of nausea and vomiting after laparoscopic cholecystectomy[J].Modern Medicine Health,2011,27(11):1617-1618.
Authors:YU Dai-di
Institution:YU Dai-di (Department of Anesthesiology,People′ s Hospital of Qiyang Country,Qiyang,Hunan 426100,China)
Abstract:Objective:To observe the effect of azasetron combined with dexamethasone in prevention of postoperative nausea and vomiting(PONV) after laparoscopic cholecystectomy.Methods:Eight patients scheduled for laparoscope cholecystectomy undergoing general anesthesia were randomly dividedly into four groups.In group A and D,the patients received normal saline before anesthetic induction,while group B and C received dexamethasone.At the end of operation,the patients received azasetron in group A and C,but patients i...
Keywords:Azasetron  Dexamethasion  Laparoscopic cholecystectomy  Nausea and vomiting  
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