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抗癫痫药物研究进展
引用本文:洪钢,章江生,王琳辉. 抗癫痫药物研究进展[J]. 中国临床药理学与治疗学, 2005, 10(11): 1201-1209
作者姓名:洪钢  章江生  王琳辉
作者单位:1. 江苏省药品认证管理中心,南京,210002,江苏
2. 康恩贝集团有限公司,杭州,310052,浙江
3. 苏州大学医学院生理学教研室,苏州,215007,江苏
摘    要:癫痫是一种由多种不同原因引起的严重脑部疾病,随着对癫痫发病机理研究的深入,更多的抗癫痫药物得以开发使用。本文分类综述了γ氨基丁酸(GABA)能药物、谷氨酸受体拮抗剂以及作用于膜离子通道、神经肽受体等靶点的抗癫痫新药。

关 键 词:癫痫  γ-氨基丁酸受体  谷氨酸受体  离子通道  神经肽
文章编号:1009-2501(2005)11-1201-09
收稿时间:2005-08-10
修稿时间:2005-09-19

Progresses in studies on anti-epileptic drugs
HONG Gang,ZHANG Jiang-sheng,WANG Lin-hui. Progresses in studies on anti-epileptic drugs[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2005, 10(11): 1201-1209
Authors:HONG Gang  ZHANG Jiang-sheng  WANG Lin-hui
Affiliation:Centre for Drug Certification of Jiangsu, Nanfing 210002, Jiangsu, China; IConba Group Co. Ltd., Hangzhou 310052, Zhejiang , China ; 2.Department of Physiology School of Medicine of Soochow University, Suzhou 215007, Jiangsu , China
Abstract:Epilepsy is a common serious brain disorder and comprises a wide range of symptom induced by varying etiologies. As more and more knowledge of mechanisms underlying seizure propagation of epilepsy gained, much more new antiepileptic-drug has been developed. In this article, we reviewed some kinds of new antiepileptic drugs used or researched in recent years.
Keywords:epilepsy  GABA-receptor  glutamate receptor  ion channel  neuropeptide  
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