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| 肌酸激酶同工酶肌钙蛋白肌红蛋白检测在新生儿窒息致心肌损害中的应用 | |
| 引用本文： | 李光荣,涂业桃. 肌酸激酶同工酶肌钙蛋白肌红蛋白检测在新生儿窒息致心肌损害中的应用[J]. 检验医学与临床, 2008, 5(23): 1421-1422 |
| 作者姓名： | 李光荣 涂业桃 |
| 作者单位： | 1. 泸州医学院附属医院,检验科,四川泸州,646000 2. 泸州医学院附属医院,输血科,四川泸州,646000 |
| 摘 要： | 目的探讨肌酸激酶同工酶（CK-MB）、心肌肌钙蛋白T（cTnT）和肌红蛋白（Mb）在新生儿窒息致心肌损害中的应用。方法采用免疫化学发光法对30例健康足月新生儿、88例窒息新生儿进行CK-MB、cTnT和Mb检测。结果窒息新生儿组CK-MB、cTnT和Mb值与健康新生儿比较均显著升高（P〈0．01），且与窒息程度呈正比。结论窒息对新生儿心肌产生损伤，CK-MB、Mb和cTnT3项指标能较好地反映心肌损害程度。 |
| 关 键 词： | 肌红蛋白 心肌肌钙蛋白T 肌酸激酶同工酶 新生儿窒息 |
The application of measurement of CK-MB,cTnT and Mb in myocardial damage complicated by apnoea neonatorum |
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| LI Guang-rong,TU Ye-tao. The application of measurement of CK-MB,cTnT and Mb in myocardial damage complicated by apnoea neonatorum[J]. Laboratory Medicine and Clinic, 2008, 5(23): 1421-1422 | |
| Authors: | LI Guang-rong TU Ye-tao |
| Affiliation: | LI Guang-rong , TU Ye-tao( 1. Department of Clinical Laboratory ; 2. Department of Blood Transfusion ,Affiliated Hospital of Luzhou Medical College, Luzhou 646000,China) |
| Abstract: | Objective To investigate the application of measurement of CK-MB,cTnT and Mb in myocardial damage complicated by apnoea neonatorum. Methods Immunochemiluminescent assay was applied to measuring CK- MB,cTnT and Mb in 30 healthy full-term newborns （healthy newborn group） and 88 newborns with asphyxia （apnoea neonatorum group）. Results The levels of CK-MB,cTnT and Mb in apnoea neonatorurn group were significantly higher than those in healthy newborn group （P〈0.01）, and the elevated levels were positively correlative to the degree of asphyxia. Conclusion The myocardial damage is partly attributable to asphyxia,and three indicators （CK- MB,cTnT and Mb） may reflect the extent of myocardial damage effectively. |
| Keywords: | myoglobin cardiac troponin T CK-MB apnoea neonatorum |
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