涤纶布修补胸壁肿瘤切除后巨大胸壁缺损46例

背景：涤纶布作为一种临床常用耗材，取材简单，价格低廉，具有较高的坚韧度及延展性，可作为一种良好的修复材料使用。目的：观察涤纶布用于巨大胸壁修补的实际疗效。方法：选择46例胸壁肿瘤患者，其中男29例，女17例，年龄39-73岁。将46例患者随机均分为观察组与对照组，观察组患者切除胸壁肿瘤后采用涤纶布修补巨大胸壁缺损，对照组采用自体带蒂侧胸壁筋膜皮瓣修补巨大胸壁缺损，记录两组患者临床疗效及患者满意度。结果与结论：术后全组病例均能胜任日常工作，无死亡及严重并发症发生，其中2例术后发生局部积液，经切口引流后好转，所有患者胸廓外观良好，呼吸运动时重建处无不适感。随访6-24个月，复查X射线片复查显示重建胸廓良好，未见移植松动、异物排斥反应、胸壁畸形等，无复发及严重并发症。观察组临床疗效及患者满意度优于对照组(P < 0.05)。结果表明涤纶布用于巨大胸壁修补的治疗，具有疗效显著、安全可靠的特点。中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程 

Polyester fabrics for repair of large chest wall defects after tumor resection in 46 cases

BACKGROUND:Polyester fabric as a common clinical consumable item is characterized by simple drawing, low cost, and high toughness and ductility, and can serve as a good repair material.OBJECTIVE:To investigate the clinical efficacy of polyester fabrics used for huge chest wall repair.METHODS:Totally 46 patients with chest wall tumors, aged 39-73 years, including 29 males and 17 females. These patients were randomly and equally divided into observation group and control group. After the removal of chest wall tumors, patients in the observation group underwent polyester fabric repair of huge chest wall defects, and those in the control group were treated with autologous pedicle flap for repair of huge chest wall defects. The clinical efficacy and patient satisfaction were recorded in the two groups.RESULTS AND CONCLUSION:After treatment, all the patients could feel up to their daily work, and there were no death and serious complications. Only two cases developed postoperative local effusion, and then recovered after wound drainage. Thoracic appearance was good in all patients, and the patients did not feel discomfort at the reconstruction site during breathing and movement. At the end of 6-24 months of follow-up, X-ray review showed good reconstruction of the thorax, and there were no loose transplants, foreign body rejection, chest wall deformity, recurrence and serious complications. Clinical efficacy and patient satisfaction were better in the  observation group than the control group (P < 0.05). These results show that polyester fabrics for the repair of huge chest wall defects are effectively, safe and reliable.