Effect of thyrocytes from transgenic mice expressing thyroid specific MHC class Ⅱ on autologous T lymphocyte in vitro |
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作者姓名: | 李玉姝 于晓会 滕晓春 关海霞 范晨玲 单忠艳 滕卫平 |
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作者单位: | 中国医科大学附属第一医院内分泌科暨内分泌研究所,沈阳,110001; |
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摘 要: | Thyrocytes expressing MHC class Ⅱ molecules were separated from transgenic mice and were co-cultured with autologous spleen T lymphocytes. T cells did not proliferate and were not activated, but CD4+ T cells were promoted into apoptosis.
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关 键 词: | 甲状腺细胞 主要组织相容性复合体Ⅱ类分子 T淋巴细胞 Major histocompatibility class Ⅱ |
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