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CD_4~+CD_(25)~+调节性T细胞与自身免疫性疾病
引用本文:郎涛,吴广胜. CD_4~+CD_(25)~+调节性T细胞与自身免疫性疾病[J]. 医学综述, 2008, 14(19): 2887-2890
作者姓名:郎涛  吴广胜
作者单位:石河子大学医学院第一附属医院血液内科,新疆,石河子,832008
摘    要:
CD4+CD2+5调节性T细胞是一群具有免疫调节或免疫抑制功能的细胞。越来越多的实验证明,CD4+CD25+调节性T细胞在维持外周免疫耐受中起重要作用,这种T细胞的数量减少或功能缺失可导致自身免疫性疾病的发生。本文就CD4+CD25+调节性T细胞及其在自身免疫性疾病中作用的研究进展进行综述。

关 键 词:CD4+CD2+5调节性T细胞  自身免疫病  免疫耐受

CD_4~+CD_(25)~+ regulatory T cell and Autoimmune Disease
LANG Tao,WU Guang-sheng. CD_4~+CD_(25)~+ regulatory T cell and Autoimmune Disease[J]. Medical Recapitulate, 2008, 14(19): 2887-2890
Authors:LANG Tao  WU Guang-sheng
Affiliation:LANG Tao,WU Guang-sheng.(Department of Hematopathy,First Affiliated Hospita,Medical College,Shihezi University,Shihezi 832008,China)
Abstract:
CD4+CD25+ regulatory T cell is a crowd of cells,which can regulate and suppress the immune response.Accumulated experiments have proved that CD4+CD25+ regulatory T cells play an important role in the maintenance of peripheral immune tolerance,and the decrease or afunction of them will result in the development of autoimmune disease.This article reviews the related research development on CD4+CD25+ regulatory T cell and its role in the autoimmune disease.
Keywords:CD4+CD25+ regulatory T cell  Autoimmune disease  Immune tolerance  
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