全角膜板层带环形结膜移植治疗严重眼表化学烧伤

目的 探讨全角膜板层带环形结膜移植治疗严重眼表化学烧伤的临床效果。方法 对11例(11眼)严重眼表化学烧伤病例，行全角膜板层带环形结膜移植术治疗并进行回顾性研究，对手术方法、时机、效果进行评估。结果 11例中，10例在术后3～7d上皮愈合，1例12d后才愈合。随访1年，全部眼表稳定，角膜透明或半透明，其中6例周边部有少量血管翳侵入，8例层间基质床有新生血管生长，仅1例眼表及角膜血管纤维化愈合。结论 全角膜板层带环形结膜移植治疗严重眼表化学烧伤，术后早期即可获得较为完整的眼表面，由于供体角膜缘干细胞所提供的新上皮，使术眼获得正常眼表型上皮，维持眼表的稳定和生理功能。主要并发症是移植排斥反应。

Total lamellar corneal and annular conjunctival transplantation for severe ocular chemical burn

Objective To observe the clinical effectiveness of total lamellar corneal and annular conjunctival transplanation for severe ocular chemical burn. Methods Eleven cases ( 11 eyes) were retrospectively analyzed to evaluate the operative method, operative timing and results. Results The epithelial healed in 10 cases during 3 to 7 days after surgery, only 1 case at twelve days post-operation. All transplantation was stabilized, cornea was transparent or semitransparent during the 1-year and 6 cases with a little panpus around, 8 cases with new vessels in interlamellar stroma, 1 case with ocular and corneal vascular fibrosis. Conclusions Total lamellar corneal with annular conjunctival transplantation is an effective way for severe ocular chemical burn , its main complication is graft rejection.