安徽省人群弓形虫感染血清流行病学调查

目的了解安徽省人群弓形虫感染状况，探索弓形虫感染的易感因素，为制定防治策略和措施提供依据。方法在安徽省南、北、中三个地区随机选择一个研究现场，采用整群抽样的方法．抽取三个地区7～75岁居民共1795人．对调查者进行弓形虫易感因素的问卷调查．并采用酶联免疫吸附试验（ELISA），检测血清中弓形虫特异抗体IgG。将调查和检测结果录入数据库．统计分析易感因素。结果共调查1795人，阳性201人，总感染率为11．20％。不同地区、性别间感染率差异无显著性意义（P〉0．05）：不同年龄组间感染率差异具有显著性意义（X2=30．27．P〈005）．其中60岁以上年龄组感染率最高为18．35％；不同文化程度各组间感染率差异具有显著性意义（X2=9．60，P〈0．05）；特殊人群（孕妇、宠物猫犬主、家畜饲养者、肿瘤患者及屠宰场工人）感染率为14．87％，显著高于普通人群（3．72％）．其相对危险度（RR）为3．99。结论安徽省弓形虫感染率在全国处于较高水平，其感染可能与接触动物的机会、生活方式及饮食习惯及自身免疫力等因素密切相关。

The serological survey of Toxoplasma infection in Anhui Province

Objective To investigate the Toxoplasma infection in Anhui province and explore the sus- ceptible factors of infection, and provide scientific evidence for making out control strategies. Methods One spot was selected randomly at southern, northern and middle district in Anhui province, respectively. The peripheral blood of the residents was collected and questionnaire surveys were undertaken by cluster sampling in the three spots. IgG antibodies to Toxoplasma were detected by ELISA. The results of detection and investiga- tion were input to analyze the susceptible factors. Results A total of 1 795 residents were detected,and 201 were positive with positive rate of 11.20%. There were no significant （P〉0.05）difference among the districts and sexualities. There was significant difference among age groups（x2=30.274, P〈0.05）,and the people over 60 years old showed the highest infection rate （18.35%）. The difference among groups with different cultural level was significant（x2=9.60,P〈0.05）. The positive rate in special population（such as pregnant women, owners of pet dogs or cats, owners of livestock, tumor patients, butchers）was 14.87% which was much higher than that of general population （3.72%）, and the relative risk （RR） was 3.99. Conclusion The overall infection rate of Toxoplosma in Anhui province was higher thai： the national average level. The prevalence of Toxoplasma was highly related to the time touching the animals, life style, diet custom and immunity.