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手足口病合并细菌感染的病原菌分布及耐药性分析
引用本文:王远方,王兆,李建萍,陈微微,万容. 手足口病合并细菌感染的病原菌分布及耐药性分析[J]. 中华医院感染学杂志, 2012, 22(20): 4656-4657
作者姓名:王远方  王兆  李建萍  陈微微  万容
作者单位:1. 遵义市第一人民医院重症医学科,贵州遵义,563002
2. 遵义市第一人民医院儿科,贵州遵义,563002
摘    要:
目的 探讨手足口病合并细菌感染的病原菌分布及其耐药性.方法 选取2009年1月-2011年12月入住ICU的重症手足口病合并细菌感染的32例患儿为研究对象,将其分离出的病原菌分布及耐药性进行调查研究.结果 32例患儿共送检64份标本,检出34株病原菌,其中大肠埃希菌、鲍氏不动杆菌及铜绿假单胞菌所占比例最高,分别占41.18%、23.53%及17.65%,其中大肠埃希菌所占比例明显高于其他病原菌;3种病原菌的耐药率最高的3种抗菌药物为头孢噻肟、头孢吡肟、头孢他啶,分别为75.00%~83.33%、62.50%~71.43%、62.50%~66.67%,差异有统计学意义(P<0.05).结论 手足口病合并细菌感染的病原菌分布及耐药性均有其特点,在诊断及治疗的过程中应给予重视.

关 键 词:手足口病  感染  病原菌  耐药性

Pathogens for bacterial infections with hand,foot, and mouth diseases and analysis of drug resistance
WANG Yuan-fang,WANG Zhao,LI Jian-ping,CHEN Wei-wei,WAN Rong. Pathogens for bacterial infections with hand,foot, and mouth diseases and analysis of drug resistance[J]. Chinese Journal of Nosocomiology, 2012, 22(20): 4656-4657
Authors:WANG Yuan-fang  WANG Zhao  LI Jian-ping  CHEN Wei-wei  WAN Rong
Affiliation:(First People′s Hospital of Zunyi,Zunyi,Guizhou 563002,China)
Abstract:
OBJECTIVE To investigate the distribution of bacterial infections of the hand,foot and mouth disease pathogens and situation of the antibiotic resistance.METHODS A total of 32 children with severe HFMD and bacterial infections from Jan 2009 to December 2011 admitted to the ICU were chosen as the research objects.The pathogen distribution and antibiotic resistance were taken for investigation.RESULTS There were 64 specimens in the 32 patients of submission,and 34 strains of pathogens were detected,including Escherichia coli,Acinetobacter baumannii and Pseudomonas aeruginosa,accounting for 41.18%,23.53% and 17.65%,the proportion of E.coli was significantly higher than that of the other pathogens.The three antibiotics with the highest drug resistance rates were cefotaxime sodium(75.00%~83.33%),cefepime(62.50%~71.43),and ceftazidime(62.50%~66.67%),the differences were statistically significant(P<0.05).CONCLUSION The distribution and drug resistance of the the pathogens causing bacterial infections with the hand,foot and mouth diseases have their own characteristics,which should be attached great importance.
Keywords:Hand,foot and mouth disease  Infection  Pathogen  Drug resistance
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