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Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) |
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| Authors: | Kristen M. Reipas Jennifer H. Law Nicole Couto Sumaiya Islam Yvonne Li Huifang Li Artem Cherkasov Karen Jung Amarpal S. Cheema Steven J.M. Jones John A. Hassell Sandra E. Dunn |
| Affiliation: | 1. Laboratory for Oncogenomic Research, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada;2. Genome Science Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.;3. Vancouver Prostate Centre, University of British Columbia, Vancouver, British Columbia, Canada.;4. Laboratory for Experimental Oncology, University of Alberta, Edmonton, Alberta.;5. Center for Functional Genomics, McMaster University, Ontario, Canada. |
| Abstract: | |
| Keywords: | Triple-negative breast cancer p90 ribosomal S6 kinase Y-box binding protein-1 tumor-initiating cells drug repositioning |