过敏性疾病患者过敏原检测及尘螨脱敏治疗观察

目的 了解过敏性疾病过敏源检测情况及粉尘螨脱敏治疗效果。方法 采用酶免疫分析法对468例过敏性疾病患者血清过敏源特异性IgE抗体进行定性检测，并给予仅对尘螨过敏的患者粉尘螨注射液脱敏治疗。结果 吸入组中粉尘螨、蟑螂、飞蛾、蜜蜂、霉菌为主要致病过敏源；食物组中虾、蟹、贝类，菇类为主要致病过敏源；粉尘螨脱敏治疗有效率为83．3％。结论 尘螨、蟑螂、飞蛾、蜜蜂、霉菌、虾、蟹、贝类为主要东莞地区过敏性疾病的主要致敏原；粉尘螨脱敏治疗有较好疗效。

The allergen distribution of the hypersensitive diseases and the observation on the result of desensitization of dust mite

Objective To find out the allergen distribution of the hypersensitive diseases and to observe the result of desensitization of dust mite. Methods The specific IgE for food and inhalant allergens were detected serologically by ELISA in the sera from 468 cases with the hypersensitive disease. The dermatophagoides farinae injection was used to desensitize the patients who were sensitive only to dust (powder) mite. Results In the inhalant allergens, the dust (powder) mite, blackbeetle, moth, bee, mildew were the main allergen. In the food allergens, shrimp, crab, shellfish, mushroom were the main allergens. The effective rate of desensitization of dust (powder) mite was 83.3%. Conclusions The dust (powder) mite, blackbeetle, moth, bee, mildew, shrimp, crab, shellfish were the main allergens in Dongguan. The treatment of desensitization of dust mite had the good effect.