505例健康体检者的中医体质类型与血糖、血脂、体质量指数关系分析

目的 研究不同体质与血脂、空腹血糖（fasting blood glucose,FBG）、体质量指数（body mass index,BMI）的关系,从宏观和微观角度探究体质的形态结构特质.方法 对505例健康体检人群进行横断面的中医体质调查,同时测定各受试者的血清总胆固醇（total cholesterol,TC）、三酰甘油（triglyceride,TG）、低密度脂蛋白（low density lipoprotein,LDL）、高密度脂蛋白（high density lipoprotein,HDL）、FBG,计算BMI,比较每种偏颇体质与平和质的TC、TG、LDL、HDL、FBG、BMI及高脂血症发生率,对每种体质的转化分与TC、TG、LDL、HDL、BMI进行多元线性回归分析.结果 阳虚质者TC、TG、BMI显著低于平和质者（P〈0.05,或P〈0.01）,痰湿质者BMI显著高于平和质者（P〈0.05）,气郁质者BMI显著低于平和质者（P〈0.01）.与平和质比较,阳虚质者高脂血症的发生率呈下降趋势,痰湿质者呈升高趋势.多元线性回归分析显示,LDL越高,阳虚质转化分越低;TG越高、BMI越大,阴虚质转化分越低,FBG越高,阴虚质转化分越高;HDL越高,痰湿质转化分越低;BMI越大,瘀血质、气郁质、特禀质转化分越低.结论 阳虚质、阴虚质、瘀血质、气郁质者体型偏瘦,痰湿质者体型偏胖;阳虚质者血TC、TG、LDL、FBG偏低,阴虚质者血FBG偏高,痰湿质者TG、LDL偏高,HDL偏低;痰湿质者具有易发高脂血症的倾向.

Relationship of Traditional Chinese Medicine Constitutions with Blood Glucose, Blood Lipids, and Body Mass Index: An analysis of 505 Healthy Cases

Objective To study the relationship of traditional Chinese medicine （TCM） constitutions with blood lipids, fasting blood glucose （FBG）, and body mass index （BMI） and to investigate the physical features of constitutions from the macroscopic and microscopic perspectives. Methods A cross-sectional study of TCM constitutions was conducted in 505 healthy persons who underwent physical examination; meanwhile, serum levels of total cholesterol （TC）, triglyceride （TG）, low-density lipoprotein （LDL）, high-density lipoprotein （HDL）, and FBG were measured, and BMI was calculated. The persons with imbalanced constitutions were compared with those with balanced constitution in terms of TC, TG, LDL, HDL, FBG, BMI, and incidence of hyperlipidemia; multivariate linear regression analysis was performed to determine the correlation between the transformed score of each constitution and the TC, TG, LDL, HDL, and BMI. Results Compared with those with normal constitution, the persons with yang deficiency constitution had significantly lower TC, TG, and BMI （P〈O. 05 or P〈0.01）, the persons with phlegm- dampness constitution had a significantly higher BMI （P〈 0. 05）, and the persons with qi-stagnation constitution bad a significantly lower BMI （P〈0.01） ; in addition, the persons with yang-deficiency con- stitution showed a decreasing trend in the incidence of hyperlipidemia, while the persons with phlegm- dampness constitution showed an increasing trend in the incidence of hyperlipidemia. The multivariate line- ar regression analysis showed that LDL was negatively correlated with the transformed score of yang-defi ciency constitution; TG and BMI were negatively correlated with the transformed score of yin-deficiency conMitution, and FBG was positively correlated with the transformed score of yin-deficiency constitution; HDL was negatively correlated with the transformed score of phlegm-dampness constitution; BMI was negatively correlated with the transformed scores of stagnant-blood constitution, qi-stagnation constitu- tion, and inherited special constitution. Conclusion The persons with yang-deficiency constitution, yin- deficiency constitution, blood stasis constitution, and qi-stagnation constitution are relatively thin, while the persons with phlegm-dampness constitution are relatively fat; the persons with yang-deficiency consti- tution have relatively low levels of TC, TG, LDL, and FBG, the persons with yin-deficiency constitution have relatively high FBG level, and the persons with phlegm dampness constitution have relatively high levels of TG and LDL and relatively low HDL level; the persons with phlegm-dampness constitution are prone to hyperlipidemia.