停供碘盐对高碘地区中混杂分布的饮用非高碘水人群碘营养水平影响的实验研究

目的探讨停供碘盐对高碘地区中混杂分布的饮用非高碘饮水人群碘营养水平的影响。方法采用现场干预试验的方法，选择饮水水碘含量5～150μg/L的居民户作为研究对象，以户为单位，进行停供碘盐现场干预，采集学龄儿童和育龄妇女干预前与干预后60天的一次随意尿样，检测其尿碘含量。结果干预60天后学龄儿童、育龄妇女的尿碘中位数分别为252．2μg／L、249．3μg／L，均较干预前显著下降（P〈0．05）；干预后学龄儿童各水碘组的尿碘中位数分别介于189．7～308．2μg／L，育龄妇女各水碘组的尿碘中位数分别介于181．1～301．7μg／L。结论停供碘盐后高碘地区饮用非高碘饮水重点人群的碘营养水平为适宜或大于适宜量。

Study on changing of iodine nutrition level of the people with unexcessive iodine drinking water in iodine excess areas after stopping supplies of iodized salt

Objective To discuss changing of iodine nutrition level of the people with unexcessive iodine drinking water in iodine excess areas after stopping supplies of iodized salt. Methods The families with 5 to 150 μg/L iodine contents in drink- ing water were chosen to substitute non - iodized salt for their current iodized salt for 2 months through field trial study, and urine samples of the target population were collected for determination of iodine change respectively before and the 60th day after the in- tervention. Results After the intervention, the median urinary iodine of school children aged 8 to 13 years was 252.2 μg/L, the median urinary iodine of women with productive age was 249.3 μg/L, the median urinary iodine of school children and women with productive age decreased significantly（ P 〈 0.05）. The median urinary iodine of school children in groups with different io- dine contents in drinking water was between 189.7 μg/L and 308.2 μg/L, and the median urinary iodine of women with produc- tive age was between 181.1 μg/L and 301.71μg/L. Conclusions The iodine nutrition level of people was adequate or more than adequate , drinking unexcessive iodine water in iodine excess areas after stopping supplies of iodized salt.