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Vitamin D deficiency is significantly associated with retinopathy in young Japanese type 1 diabetic patients
Affiliation:1. Department of Metabolic Medicine, Osaka University, Graduate School of Medicine, Osaka, Japan;2. Clinical Research Center for Diabetes, Tokushima University, Tokushima, Japan;3. Department of Internal Medicine, Osaka Police Hospital, Osaka, Japan;1. The Renal Data Registry Committee, The Japanese Society for Dialysis Therapy, Tokyo, Japan;2. Division of Nephrology, Hypertension and Endocrinology, Nihon University School of Medicine, Tokyo, Japan;3. Department of Comprehensive Kidney Disease Research, Osaka University Graduate School of Medicine, Osaka, Japan;4. Nephrology Center, Toranomon Hospital, Tokyo, Japan;5. Department of Nephrology, Kitasaito Hospital, Asahikawa, Japan;6. Department of Metabolism, Endocrinology, and Molecular Medicine, Osaka City University, Osaka, Japan;7. Department of Clinical Engineering, Fujita Health University, Aichi, Japan;8. Department of Nephrology, Yabuki Hospital, Yamagata, Japan;1. Endocrinology Unit-Hospital de Clínicas de Porto Alegre, Postgraduate Fellowship Program in Endocrinology-Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil;2. Centro de Endocrinologia do Estado da Bahia (CEDEBA), Salvador, Brazil;3. Universidade do Estado da Bahia (UNEB), Salvador, Brazil;4. Pediatric Endocrinology Unit, Santa Casa de Misericórdia, São Paulo, Brazil;5. Instituto da Criança, Hospital das Clínicas, Universidade de São Paulo (USP), Brazil;6. Laboratory of Molecular and Translacional Endocrinology, Universidade Federal de São Paulo (UNIFESP), Brazil;7. Diabetes Center, Universidade Federal de São Paulo (UNIFESP), Brazil;1. The Save Sight Institute, Sydney Medical School, The University of Sydney, Sydney, New South Wales;2. Department of Ophthalmology, Gui De Chauliac Hospital, Montpellier, France;3. Inserm, U1061, Montpellier, France;4. Academic Unit of Ophthalmology, Australian National University, Acton, Australian Capital Territory;5. Department of Population Health, University of Western Australia, Perth, Western Australia;6. Department of Ophthalmology, University Hospital Zurich, University of Zurich, Zurich, Switzerland;1. Department of Clinical Nursing, Shiga University of Medical Science, Tsukinowa-cho Seta, Otsu, Shiga 520-2192, Japan;2. Department of Mathematical Health Science, Graduate School of Medicine, Osaka University, 1-7 Yamadaoka, Suita, Osaka 565-0871, Japan;3. Saku Central Hospital, 197 Usuda, Saku, Nagano 384-0301, Japan
Abstract:The aim of this study was to examine the possible association of vitamin D deficiency with diabetic retinopathy in 75 young Japanese type 1 diabetic patients. A multivariate regression analysis, duration of diabetes and vitamin D deficiency were independent determinants of diabetic retinopathy.
Keywords:Vitamin D deficiency  Type 1 diabetes  Retinopathy
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