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| FK506致肝功能异常2例并文献复习 | |
| 引用本文： | 李金庆,马潞林,赵磊,张树栋,候小飞,王国良,罗康平. FK506致肝功能异常2例并文献复习[J]. 临床医学, 2007, 27(11): 5-7 |
| 作者姓名： | 李金庆 马潞林 赵磊 张树栋 候小飞 王国良 罗康平 |
| 作者单位： | 青岛大学医学院第二附属医院泌尿外科,青岛,266042;北京大学第三医院泌尿外科 |
| 摘 要： | 目的探讨FK506的肝毒性。方法报告2例肾移植术后应用FK506后,出现转氨酶、胆红素升高。结果1例仅停药后肝功恢复;另1例经停药,保肝治疗后恢复。结论FK506可引起肝脏损害,致转氨酶、胆红素升高,临床应用中注意该项副作用。 |
| 关 键 词： | FK506 肝毒性 药物副作用 |
| 修稿时间： | 2007-08-06 |
Fk506 caused 2 cases liver damage after kidney transplantation and review of literature |
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| LI Jinqing,MA Lulin,ZHAO Lei,ZHANG Shudong,HOU Xiaofei,WANG Guoliang,LUO Kangping. Fk506 caused 2 cases liver damage after kidney transplantation and review of literature[J]. Clinical Medicine, 2007, 27(11): 5-7 | |
| Authors: | LI Jinqing MA Lulin ZHAO Lei ZHANG Shudong HOU Xiaofei WANG Guoliang LUO Kangping |
| Affiliation: | 1.Department of Urology ,the Secoad Affili- ated Hospital of Qingdao University Medical College, Qingdao 266042, Shandong ; 2 . Department of Urology, the Third Hospital of Peking University |
| Abstract: | Objective To discuss the drug-induced liver damage by FK506.Methods Clinical data of 2 cases whose alanine aminotransferase(ALT),bilirubin(T-Bil) elevating with oral take FK506 after renal transplantation had been analysed.Results One patient's hepatic function had returned normal after stopping FK506;the other had returned normal after stopping FK506 and giving liver-protective remedies.Conclusion FK506 may cause liver damage and liver function,so they should be monitored in renal recipients particularly. |
| Keywords: | Tacrolimus Hepatotocxicity Adverse drug reactions |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |